Examples of Our Work
The Aging Biomarkers Core team is actively involved in research projects with departments across The Ohio State University and at outside universities and entities across the country. This keeps us engaged with the latest technology and gives us the experience needed to better understand your own research expectations.
As integral members of a research team, we're able to offer testing suggestions, support and feedback during research design through completion and publication.
Below is a list of recent studies we've supported. This is not an exhaustive list, so if there is a specific medical specialty or research format you'd like to confirm our experience with, please let us know so we can share additional examples.
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Determining the relationship of p16INK4a and additional molecular markers of aging with clinical frailty in hematologic malignancy.
Rosko AE, Elsaid MI, Woyach J, Islam N, Lepola N, Urrutia J, Christian LM, Presley C, Mims A, Burd CE. J Cancer Surviv. 2024 Aug;18(4):1168-1178. doi: 10.1007/s11764-024-01591-6. Epub 2024 Apr 28. PMID: 38678524; PMCID: PMC11324703.
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Gut microbiota richness and diversity track with T cell aging in healthy adults.
Madison AA, Burd CE, Andridge R, Wilson SJ, Bailey MT, Belury MA, Spakowicz DJ, Malarkey WB, Kiecolt-Glaser JK. J Gerontol A Biol Sci Med Sci. 2024 Mar 1;79(3):glad276. doi: 10.1093/gerona/glad276. PMID: 38123141; PMCID: PMC10878250.
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Peripheral blood CD3+ T-cell gene expression biomarkers correlate with clinical frailty in patients with haematological malignancies.
Fell G, Rosko AE, Abel GA, Dumontier C, Higby KJ, Murillo A, Neuberg DS, Burd CE, Lane AA. Br J Haematol. 2022 Oct;199(1):100-105. doi: 10.1111/bjh.18336. Epub 2022 Jun 29. PMID: 35766906; PMCID: PMC10462450.
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Impact of age-related T cell dynamics on the identification of biomarkers predictive of immunotherapy discontinuation: a prospective cohort study.
Galloway JE, Holderbaum AM, Arya N, Zhang S, Bodnar MS, Norman R, Carson WE, Yu L, Kendra KL, Burd CE. Aging Cancer. 2020 Dec;1(1-4):58-70. doi: 10.1002/aac2.12012. Epub 2020 Sep 17. PMID: 34337428; PMCID: PMC8323507.
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Association of epigenetic age and p16INK4a with Markers of T-cell composition in a healthy cohort.
Burd CE, Peng J, Laskowski BF, Hollyfield JL, Zhang S, Fadda P, Yu L, Andridge RR, Kiecolt-Glaser JK. J Gerontol A Biol Sci Med Sci. 2020 Nov 13;75(12):2299-2303. doi: 10.1093/gerona/glaa108. PMID: 32361724; PMCID: PMC7662168.
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T Cell transcriptional profiling and immunophenotyping uncover LAG3 as a potential significant target of immune modulation in multiple myeloma.
Lucas F, Pennell M, Huang Y, Benson DM, Efebera YA, Chaudhry M, Hughes T, Woyach JA, Byrd JC, Zhang S, Jones D, Guan X, Burd CE, Rosko AE. Biol Blood Marrow Transplant. 2020 Jan;26(1):7-15. doi: 10.1016/j.bbmt.2019.08.009. Epub 2019 Aug 21. PMID: 31445183; PMCID: PMC6952061.